TruCBN™ — The Next Generation Sleep Ingredient

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“TruCBN™ is the most innovative new sleep ingredient available on the market today.”
- Matthew Roberts, Ph.D

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Redefining sleep

TruCBN™ ushers in a new era of natural sleep products that are non-hormonal, non-habit-forming, and proven to restore both mind and body.

Proven effective

In a double-blind, placebo-controlled clinical trial with over 1,000 adults, TruCBN™ was shown to significantly improve sleep quality and duration without intoxication or next-day effects.

Therapeutic potential

Emerging research shows CBN’s benefits extend beyond sleep, supporting neuroprotection and healthy brain function through its antioxidant and mitochondrial-stabilizing effects.

Market ready

TruCBN™ is the only CBN ingredient backed by a full GLP toxicology studies and prepped for an FDA GRAS filing in Q4 2025.

Why it matters

The need for safe, effective sleep solutions has never been greater. TruCBN™ was developed to meet this demand: clinically proven, non-habit forming, and supported by rigorous safety data.

The sleep crisis is getting worse

Over 70 million Americans suffer from chronic sleep problems and a massive 33% of  adults regularly report inadequate sleep.

Restorative sleep is the solution

Restorative sleep is the key to long-term health. It supports immunity, improved cognition, mood and longevity.

People deserve better options

Frustration with melatonin and pharma-driven solutions is driving demand for non-hormonal, non-habit forming ingredients that deliver meaningful results.

TruCBN™ is proven safe & effective

TruCBN™ is the only cannabinoid clinically proven in humans and backed by full GLP safety data—offering brands a credible, differentiated sleep solution.

TruCBN™: The science of restorative sleep

The TruCBN™ sleep study demonstrated statistically significant improvements in sleep quality, duration, and restorative rest compared to placebo, without intoxication or next-day grogginess.
Clinically proven in a 6-week, randomized, double-blind, placebo-controlled trial of 1,020 adults.
Showed statistically significant improvements in both sleep quality and duration, with no intoxication and no adverse effects.
Effective at 25 mg, 50 mg doses.
50 mg TruCBN™ outperformed melatonin in sleep quality, with fewer reports of grogginess.
Read the Sleep Study

Protecting brain cells with CBN

Beyond sleep, TruCBN™ demonstrates neuroprotective benefits that may support cognitive health and healthy aging.
Preclinical studies show CBN helps protect neurons and mitochondria, supporting long-term brain health.
Multiple protective pathways:
Shields neurons from oxidative stress and ferroptosis (cell death).
Improves mitochondrial energy production (ATP), supporting cellular vitality.
Helps regulate neuroinflammation, maintaining healthy brain signaling.
Explore the Brain Health Study

Safety & tolerability

Safety is foundational to every FloraWorks discovery. TruCBN™ meets the highest scientific and regulatory standards for ingredient validation and consumer trust.

Only CBN ingredient with full GLP toxicology & genotoxicity data

Including 90-day OECD 408 study showing no adverse findings, plus negative Ames and micronucleus assays.

No adverse events found

During our 6 week human clinical study, no increase in adverse events vs. placebo was found; reported events were mild and transient.

Validated analytical methods (GLP HPLC)

Validated analytical methods (GLP HPLC) confirmed dose accuracy, precision, and stability across all studies.

Regulatory-ready

Comprehensive safety margin underpins FDA NDI and GRAS pathways, giving brands confidence in compliance and scalability.

How TruCBN™ works

TruCBN™ engages multiple biological pathways that naturally regulate sleep, mood, and neural balance, without intoxication.
Endocannabinoid modulation: Encourages natural sedation without intoxication.
Serotonin pathway influence: Supports circadian rhythm balance.
TRP channel modulation: Helps calm the nervous system and reduce sleep onset latency.
Neuroprotective activity: Preclinical studies highlight antioxidant and anti-inflammatory effects that may support long-term brain resilience.

The opportunity now

TruCBN™ marks a breakthrough moment where validated cannabinoid science meets surging consumer demand for sleep aid alternatives.
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Unlike any other ingredient available today, TruCBN™ creates a new uncontested market for mainstream supplement brands who are ready to innovate.
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Product formats & dosing guidance

TruCBN™ is available in multiple delivery formats, enabling flexible formulation across supplements, beverages, and functional foods.

Gummies

25 mg per serving supports restorative sleep.

Extra Strength Softgels or Tablets

50 TruCBN™ provides clinically meaningful, restorative outcomes.

Drink Mix

High bio-availability with TruCBN™ emulsions; easily stacked with calming co-actives.

The new sleep ingredient already making headlines

See More TruCBN™ News

Why Choose TruCBN™?

TruCBN™ is more than just an ingredient—it's a powerful sleep aid with beneficial effects you can confidently offer to your customers.

You Need Consumer Trust

92% of consumers seek products with clinical validation because they trust scientific proof over mere advertising claims.

*Source: Consumer Trends Report 2024, Citrus Labs

You Want Expanded Sales Channels

The majority of large retailers are now requiring safety and efficacy studies, only opening up shelf space for supplements with scientifically backed claims.

You Require Validated Marketing Claims

Finally a cannabinoid ingredient that can boldly make marketing claims that inspire confidence in your company and your products.

Get TruCBN™ Now

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